Men who take female hormones may notice:

• increased breast size
• feminization of body shape
• darkening of nipples
• less acne
• more feminine complexion
• slower growth of facial hair
• slower progression of baldness
• reduced chance of heart attack
• lowered risk of prostate cancer

They probably will:

• increase their risk of breast cancer
• increase the chance of blood clots which can be fatal
• increase the chance of liver or gall bladder disease or tumors
• decrease the size of their testicles
• lower their interest in sex
• alter their mood or personality in unpredictable ways